SKIN CONCERNS: ADULT ACNE, BLEMISHES, EXCESS SEBUM, ENLARGED PORES, POST-INFLAMMATORY HYPERPIGMENTATION, UNEVEN TEXTURE, WRINKLES AND LOSS OF FIRMNESS
ACTION: REDUCES THE APPEARANCE OF BLEMISHES; HELPS REGULATE SEBUM; SUPPORTS EPIDERMAL RENEWAL; SMOOTHES UNEVEN TEXTURE; HELPS CORRECT HYPERPIGMENTATION AND SIGNS OF AGEING
SKIN TYPE: OILY AND COMBINATION SKIN WITH ADULT ACNE; FOR USERS WITH ESTABLISHED RETINOID TOLERANCE
SKINCARE STEP: RETINOID CORRECTION AND RENEWAL. APPLY THE CREAM IN THE EVENING TO CLEANSED AND TONED SKIN. INTRODUCE GRADUALLY AND USE HIGH SUN PROTECTION IN THE MORNING.
CLERA ULTIMA 0.1% is an advanced cream with encapsulated retinal, developed for mature, oily skin prone to adult acne. Its multi-action formula helps reduce blemishes and excess sebum while supporting epidermal renewal, smoothing uneven texture and reducing the appearance of signs of ageing. Encapsulation improves retinal stability and enables a more controlled release. Lactoferrin and the SP[AI]3 peptide support the balance of blemish-prone skin, while glucosyl naringin provides soothing and antioxidant benefits. Calcium nano-hydroxyapatite supports skin structure and elasticity. With regular use, the complexion appears smoother, more even and visibly clearer.
How does the CLERA ULTIMA 0.1% formula work?
Who is it for?
oily and combination skin with adult acne; for users with established retinoid tolerance
Apply in the evening to cleansed and toned skin. Introduce gradually, initially using 2–3 times a week. During the day, use high sun protection.
Warnings: Contains vitamin A. Consider your daily intake from all sources before use.
The retinal encapsulation technology uses biomimetic phospholipid micelles based on hydrated lecithin, which form stable nanostructures with amphiphilic architecture. The hydrophobic core of the micelles (lipid tails) promotes the incorporation of lipophilic retinal molecules, while the hydrophilic shell allows the system to remain in stable dispersion in an aqueous environment. Due to the limited stability of retinal in classic formulations, micellar technology is a justified approach to its delivery while maintaining high skin compatibility. The biomimetic similarity of lecithin phospholipids to the building blocks of the hydrolipid barrier may promote the integration of nanostructures with skin structures and the deposition of the active substance within the epidermis. The presence of stable nanostructures and their size (on average approx. 50 nm) have been confirmed by transmission electron microscopy (TEM).
Author: Prof. Ewa Olędzka, PhD, Eng. Medical University of Warsaw
1. Stabilisation of the active substance in the formulation: incorporation of retinal into the hydrophobic core of the micelles helps to reduce exposure to degrading factors (light, shade, moisture).
2. Controlled release: micellar technology helps reduce uncontrolled, rapid release of the substance after application, which can translate into a more controlled and prolonged action profile
3. Skin compatibility: the biomimetic similarity of lecithin phospholipids to the building blocks of the skin's hydrolipid barrier may promote the integration of nanostructures into skin structures.
4. Potential support for deposition within the epidermis: interactions between the phospholipid carrier and the epidermal barrier lipids may promote the deposition of the active substance within the epidermis.
5. Better skin tolerance: the stabilisation of retinal in the formulation and controlled release may promote better tolerance compared to classic retinoid formulations.
6. Multi-level correction of photoageing symptoms: retinal, the biologically active form of retinoid, promotes the induction of structural protein synthesis and stimulates cell renewal, which can translate into improved skin texture and an even skin tone.
rewitalizujący i intensywnie ujędrniający balsam do ciała
rewitalizujący i intensywnie ujędrniający balsam do ciała
rewitalizujący i intensywnie ujędrniający balsam do ciała
rewitalizujący i intensywnie ujędrniający balsam do ciała
The 0.2% serum is intended for advanced retinoid users. We recommend it only if your skin already has a high tolerance – for example, you’ve been using 0.06% or a prescription retinoid comfortably – and you’re seeking maximum anti-ageing results. 0.2% retinal is a very potent treatment: it can significantly smooth wrinkles, firm and thicken the skin, and accelerate cell renewal. Thanks to a carefully designed formula (retinal encapsulated in lecithin, plus EGF, glucosyl naringin, and calcium hydroxyapatite), this high strength is surprisingly well-tolerated; however, we advise it only for skin that’s been “trained” on milder retinoids to avoid irritation
Introduce the highest strength very slowly and cautiously. Even if you used 0.06% every night, with 0.2% you should begin with one application per week. For example, use it just once in week 1, then twice in week 2 (with several days off in between). If everything looks good, in week 3 try every other night. Only after about a month, with no major irritation, might you use it nightly. On the off-nights, give your skin extra TLC – apply a rich, repairing moisturiser to help it recover. And as always with retinoids, use a broad-spectrum SPF 50 every morning – this is especially crucial with such a strong treatment.
Despite its strength, ETERNA FORTE is engineered to minimise irritation as much as possible. Firstly, the 0.2% retinal is encapsulated in lecithin microspheres, which ensures a slow, controlled release rather than a sudden dose on the skin. Secondly, the serum includes soothing and supportive ingredients: EGF to speed up skin repair, glucosyl naringin as a powerful antioxidant and anti-inflammatory (to reduce redness), and nano calcium hydroxyapatite to reinforce skin structure and act as a buffer for retinal delivery. Thanks to this advanced formula, 0.2% can deliver maximum anti-ageing benefits with surprisingly good tolerability. Of course, everyone’s skin is different – if you do experience excessive irritation, use it less often and keep your skin moisturised and calm between applications.
The 0.2% serum offers the most dramatic results of the ETERNA line. Initial improvements (smoother, brighter skin) can often be seen after about 4–6 weeks of consistent use. Deeper changes like reduction in more pronounced wrinkles and significant fading of dark spots usually become visible around the 3-month mark – with regular use, skin firmness improves and lines diminish as collagen builds up. By ~6 months, the anti-ageing effects are even more impressive: your skin can look noticeably rejuvenated and healthier (thanks to the profound cellular remodeling happening under the surface). Remember, a high concentration retinal is “a marathon, not a sprint” – it yields tremendous benefits, but only with sustained, long-term use. The payoff for your patience is a major improvement in your skin’s appearance and texture.
You can use 0.2% all year round, provided you protect your skin from the sun meticulously. The idea that you must stop retinoids in summer is a myth – dermatologists confirm that with proper UV protection, you can continue treatment 12 months a year . The crucial part is daily sunscreen and avoiding excessive sun exposure. In summer, consider a few tweaks: if you’re spending lots of time outdoors, you might reduce the frequency of 0.2% applications (for example, use it 2 nights a week instead of every night) or switch to a lower strength temporarily . And never apply retinal on sunburned or very sun-sensitive days. Overall, though, sticking with retinal year-round – coupled with vigilant SPF use – will give you the best, long-term anti-ageing results, as you’re not pausing the benefits.
We are happy to answer any questions about our products or other general inquiries.
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